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目的探讨直肠癌肝转移的手术治疗效果。方法分析186例直肠癌肝转移的临床资料,96例行直肠癌根治术的同时Ⅰ期行肝切除术,同时行FOLFOX方案化疗或TPVCE介入治疗;90例未切肝组行直肠癌根治性切除术,后行FOLFOX方案化疗或TPVCE介入治疗,联合放疗12例,20例联合术中瘤体注射无水酒精,分析手术效果及术后生存率。结果两组生存率差异有统计学意义(P<0.05)。结论以手术为主的联合术后化疗综合治疗是直肠癌肝转移患者的有效治疗方法
Objective To investigate the surgical treatment of liver metastasis of rectal cancer. Methods The clinical data of 186 patients with liver metastasis from rectal cancer were analyzed. 96 patients undergoing radical resection of the rectum were treated with hepatectomy and FOLFOX chemotherapy or TPVCE interventional therapy. The radical resection of rectal cancer The patients were treated with FOLFOX regimen or TPVCE interventional therapy. Twelve cases were combined with radiotherapy and 20 cases were treated with intraoperative tumor injection of anhydrous alcohol. The operative effect and postoperative survival rate were analyzed. Results There was a significant difference in survival between the two groups (P <0.05). Conclusion The combined surgery-based chemotherapy combined with postoperative chemotherapy is an effective treatment for patients with liver metastasis of rectal cancer