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One new cucurbitane-type triterpenoid saponin, 5β,19-epoxycucurbita-6,23-diene-3β,19,25-triol-3-O-β-D-allopyranoside (1),named momordicoside P was isolated from the fresh fruits ofMomordica charantia. The structure of the saponin was elucidated by spectral methods, including 2D-NMR spectra.(C) 2007 Yu Ying Zhao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.