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目的探讨甲状腺全切术治疗原发性甲状腺功能亢进症合并甲状腺癌的临床效果。方法选取我院100例原发性甲状腺功能亢进症合并甲状腺癌的患者,随机分为两组,观察组50例用甲状腺全切术治疗,对照组50例用传统甲状腺双侧叶次全切除术治疗,比较两组的临床疗效。结果甲状腺全切除手术组无术后出血病例,无甲亢复发病例,术后均合并甲减;而甲状腺双侧叶次全切除手术组术后出血率和甲亢复发率分别为4%和27%,术后出现甲减22(44%)例。两组术后均无永久性甲状旁腺功能低下并发症,喉返神经损伤发生率无明显差异(P<0.0 5)。结论甲状腺全切除术治疗甲状腺功能亢进症合并甲状腺癌的效果优于次全切除术,且其并发症总发生率和复发率低于后者。
Objective To explore the clinical effect of total thyroidectomy in the treatment of primary hyperthyroidism complicated with thyroid cancer. Methods One hundred patients with primary hyperthyroidism complicated with thyroid cancer in our hospital were randomly divided into two groups. 50 patients in the observation group were treated with total thyroidectomy and 50 patients in the control group were treated with conventional bilateral thyroidectomy. Treatment, comparing the clinical efficacy of the two groups. Results There was no postoperative bleeding in the total thyroidectomy group, no recurrence of hyperthyroidism, and postoperative hypothyroidism. The postoperative bleeding rate and the recurrence rate of hyperthyroidism in the thyroid bilateral subtotal resection group were 4% and 27%, respectively. Postoperative hypothyroidism occurred in 22 (44%) cases. There were no permanent hypoparathyroid complications after surgery in both groups, and there was no significant difference in the incidence of recurrent laryngeal nerve injury (P < 0.05). Conclusion Total thyroidectomy is superior to subtotal resection in the treatment of hyperthyroidism complicated with thyroid cancer. The total incidence and recurrence rate of complications are lower than the latter.