SYNTHESIS OF 4-SUBSTITUTED (OR 4-SPIRO) 3-OXABICYCLO[3.1.0]HEXAN-2-ONE

• 出 处: Chinese Chemical Letters
• 发表日期: 1991年11期
• 关键词: ANHYDRIDE SUBSTITUTED SPIRO ALKYL HEXANE BENZYL converted reagent membered bromo

Cyclopropanedicarboxylic anhydride can be converted to 4-substituted (or 4-spiro-)3-oxabicyclo[3.1.0]hexan-2-one by addition of Grignard (or α,ω-di-Crignard) reagents in ether or tetrahydrofuran solution.