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目的探讨不同药物治疗不稳定型心绞痛的临床效果。方法回顾性分析66例不稳定型心绞痛患者的临床治疗。随机将病例分成尼可地尔组和硝酸甘油组,尼可地尔组口服尼可地尔片,硝酸甘油组静脉注射硝酸甘油,分析对比两组的心绞痛改善情况及随访6个月的心血管事件发生率。结果两组心绞痛改善的发生率比较有统计学差异(P<0.05);治疗7d后,两组静息心电图的改善率有统计学差异(P<0.05);随访心血管事件发生率,两组无统计学差异(P>0.05)。结论尼可地尔片在控制心绞痛症及改善心电图方面要优于静脉注射硝酸甘油,同时其安全性高、不良反应少也是硝酸甘油无法比拟的。
Objective To investigate the clinical effects of different drugs in the treatment of unstable angina pectoris. Methods The clinical data of 66 patients with unstable angina pectoris were retrospectively analyzed. The patients were randomly divided into nicorandil group and nitroglycerin group, nicorandil group nicorandil tablets, nitroglycerin group intravenous nitroglycerin, analysis of angina improved compared with the two groups and followed up for 6 months of cardiovascular Incident rate. Results The improvement rates of angina pectoris in both groups were statistically significant (P <0.05). After 7 days of treatment, there was a significant difference in the improvement rate of resting electrocardiogram between the two groups (P <0.05). The incidence of cardiovascular events, No statistical difference (P> 0.05). Conclusion Nicorandil tablets are better than intravenous nitroglycerin in controlling angina pectoris and improving electrocardiogram. At the same time, nicorandil tablets have higher safety and less adverse reactions than nitroglycerin.