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该文旨在研究接受放疗并发生放射性颌骨骨坏死(ORNJ)的头颈癌患者的相关危险因素,尤其是接受某种药物治疗后及牙的变化情况。23,527例头颈癌患者纳入研究,Cox比例风险模型用于危险因素分析。结果:ORNJ的总发生率为3.93/100人/年,颊癌患者发生ORNJ的风险最高。皮质醇激素能够起到保护作用。放疗前拔牙不会增加ORNJ的风险,放
The aim of this study was to investigate the risk factors associated with head and neck cancer in patients receiving radiotherapy and osteonecrosis of the radiated jaw (ORNJ), especially after certain medical treatments and changes in the teeth. Totally 23,527 patients with head and neck cancer were included in the study and the Cox proportional hazard model was used for risk factor analysis. Results: The overall incidence of ORNJ was 3.93 / 100 person-years. The risk of ORNJ was the highest in patients with cheek cancer. Cortisol can play a protective role. Tooth extraction before radiotherapy will not increase the risk of ORNJ, put