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目的:分析腹腔镜辅助下阑尾切除术治疗不同病理类型的急性阑尾炎的效果与安全性。方法:随机抽取郑州大学第一附属医院2018年3月至2019年12月收治的不同病理类型急性阑尾炎患儿100例。根据病理类型将其分成A、B、C组。单纯急性阑尾炎患儿57例纳入A组,阑尾穿孔继发全腹膜炎患儿21例纳入B组,阑尾周围脓肿形成患儿22例纳入C组。A组接受腹腔镜下阑尾切除术治疗,B组接受腹腔镜下腹腔脓肿引流术加阑尾切除术治疗,C组接受腹腔镜下腹腔脓肿引流+肠粘连松解+阑尾切除术治疗。比较三组患儿手术指标、炎性因子水平、并发症及胃肠道恢复情况。结果:三组患儿手术时间及出血量比较差异有统计学意义(n P0.05)。A组患儿手术时间、出血量及住院时间最少,C组患儿手术及住院时间最长、出血量最多。术前,三组患儿高敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)水平比较差异未见统计学意义(n P>0.05);术后,三组患儿hs-CRP、IL-6水平比较差异有统计学意义(n P0.05)。三组患儿肠鸣音恢复时间、肛门排气时间、肛门排便时间比较差异有统计学意义(n P0.05), which were the highest in group A, followed by group B and group C, with statistic difference (n P0.05). Recovery time of bowel sounds, anal exhaust time, and anal defecation was the shortest in group C, followed by group B and group C, with statistic difference (n P<0.05).n Conclusions:Laparoscopic-assisted appendectomy for acute appendicitis of different pathological types has the similar safety and hospital stay length, but the operation time, blood loss, and inflammatory factor levels are various, so the clinical treatment should be selected based on patients’ condition.