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目的探讨高压氧联合丁咯地尔注射液对2型糖尿病周围神经病变的治疗效果。方法 82例患者随机分为两组,治疗组(42例),对照组(40例)。在降血糖的基础上治疗组应用丁咯地尔注射液加高压氧,对照组单用丁咯地尔,对两组的临床疗效进行评价。结果对照组总有效率为67.5%,治疗组总有效率为83.33%,两组总有效率比较差异有统计学意义(P<0.05);两组患者治疗后,尺神经和腓神经的运动神经传导速度、感觉神经传导速度均显著增加,与治疗前比较差异有统计学意义(P<0.05),治疗组变化更为明显。结论高压氧丁咯地尔联合应用是治疗糖尿病周围神经病变的有效方法。
Objective To investigate the therapeutic effect of hyperbaric oxygen combined with buflomedil injection on type 2 diabetic peripheral neuropathy. Methods 82 patients were randomly divided into two groups: treatment group (42 cases) and control group (40 cases). The treatment group on the basis of hypoglycemic buflomedil injection plus hyperbaric oxygen, the control group buflomedil alone, the clinical efficacy of the two groups were evaluated. Results The total effective rate of the control group was 67.5%, the total effective rate of the treatment group was 83.33%, the total effective rate was significantly different between the two groups (P <0.05). After treatment, the motor nerve of the ulnar nerve and the peroneal nerve The conduction velocity and sensory nerve conduction velocity increased significantly, which was significantly different from that before treatment (P <0.05). The changes in the treatment group were more obvious. Conclusion The combination of HBO and buprenorphine is an effective method for the treatment of diabetic peripheral neuropathy.