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目的分析人生长激素治疗儿童垂体性侏儒症疗效。方法对来福建省妇幼保健院矮身材专科就诊的矮小症患者并诊断为生长激素缺乏症31例应用生长激素进行治疗。结果治疗前后进行比较:治疗前生长速度为(2.9±0.7)cm/年,治疗后3个月生长速度为(13.5±3.7)cm/年,6个月为(13.4±3.6)cm/年,生长速度提高4倍多,治疗前后生长速度差异有统计学意义。身高由治疗前为(116±13)cm,治疗后3个月达到(120.1±12.9)cm,6个月时(123.1±13.0)cm。结论治疗过程未发现副作用。说明国产生长激素可以与国外产品相比,且安全性好,可以在临床推广应用。
Objective To analyze the curative effect of human growth hormone on pituitary dwarfism in children. Methods 31 patients with short stature who came to Fujian Maternal and Child Health Hospital for short stature were diagnosed as growth hormone deficiency and treated with growth hormone. Results Before and after treatment, the growth rate was (2.9 ± 0.7) cm / year before treatment, (13.5 ± 3.7) cm / year at 3 months after treatment, (13.4 ± 3.6) cm / year at 6 months, Growth rate increased more than 4 times, before and after treatment, the growth rate difference was statistically significant. The height was (116 ± 13) cm before treatment, 120.1 ± 12.9 cm at 3 months and 123.1 ± 13.0 cm at 6 months. Conclusion No side effects were found during the course of treatment. Description of domestic growth hormone compared with foreign products, and good safety, can be popularized in the clinical application.