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ALIMTA(premetrexeddisodium)是一种多靶向抗叶酸药 (MTA) ,可抑制多种叶酸代谢酶而发挥抗癌作用。研究发现其抗瘤谱广 ,对许多实体瘤疗效确切。现综述其抗癌机制及临床研究最新进展。
ALIMTA (premetrexeddisodium) is a multi-targeted antifolate (MTA) that inhibits a variety of folic acid-metabolizing enzymes and exerts anti-cancer effects. The study found that its broad anti-tumor spectrum, the exact effect on many solid tumors. Now review its anticancer mechanism and the latest clinical research.