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目的了解豫北社区不同诊断年龄食管癌患者生存质量(QOL)状况,为食管癌患者实施个性化护理提供理论依据。方法采用便利取样法选取豫北社会951例食管癌患者进行问卷调查和访谈。调查问卷包括一般资料调查表、欧洲癌症研究与治疗组织研制的生存质量核心量表第3版(EORTC QLQ-C30 V3.0)、食管癌补充模式量表(QLQ OES-18)。将患者按诊断年龄分为:青年组(≤44岁)、中年组(45~59岁)、年轻老年组(60~74岁)、老年组(≥75岁)。结果青年组患者与中年组和年轻老年组患者在食欲下降方面的差异有统计学意义(P﹤0.05);年轻老年组和老年组患者在生理功能方面与青年组和中年组患者差异均有统计学意义(P﹤0.05);老年组患者在认知功能、社会功能、进食3个方面与其他3组患者差异均有统计学意义(P﹤0.05)。结论不同诊断年龄对于食管癌患者生存质量的影响,主要表现在生理功能、认知功能、社会功能、进食以及食欲方面。
Objective To understand the quality of life (QOL) in patients with esophageal cancer of different diagnostic ages in the community of northern Henan and provide a theoretical basis for the implementation of personalized care in patients with esophageal cancer. Methods A total of 951 patients with esophageal cancer in North Henan were enrolled in this study by questionnaire and interviews. The questionnaire included the General Information Questionnaire, the EORTC QLQ-C30 V3.0 and the QLQ OES-18 Core Scale for Quality of Life by the European Organization for Research and Treatment of Cancer. Patients were divided according to age of diagnosis: young group (≤ 44 years old), middle age group (45 ~ 59 years old), young elderly group (60 ~ 74 years old), elderly group (≥75 years old). Results There was a significant difference in appetite loss between young patients and middle-aged patients and young patients (P <0.05). The differences between young and old patients were statistically significant (P <0.05). There were significant differences in cognitive function, social function and eating among the three elderly patients (P <0.05). Conclusions The impact of different diagnostic ages on the quality of life of patients with esophageal cancer is mainly manifested in physiological functions, cognitive functions, social functions, eating habits and appetite.