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目的:探讨心力衰竭(心衰)患者血浆脑钠素(BNP)水平与6min步行试验的相关性,进一步说明BNP测定对心衰的重要性。方法:随机选择106例住院心衰患者及65例无器质性心脏病患者作为研究对象。入院当日采集血标本以备血浆BNP、血糖、血脂等检查,并于当日完成6min步行试验。采用ELISA法测定血浆BNP水平。血浆BNP水平与6min步行距离的相关性采用SPSS for Windows V10.0软件包分析。结果:随着心衰程度的加重,血浆BNP水平逐渐升高,与6min步行距离具有良好的相关性(r=-0.804,P<0.01)。结论:血浆BNP水平可以判断心衰患者的严重程度,与6min步行试验相比,具有更广泛的临床应用价值。
Objective: To investigate the correlation between plasma BNP level and 6-minute walking test in patients with heart failure (CHF), and to further elucidate the importance of BNP in heart failure. Methods: A total of 106 hospitalized HF patients and 65 non-structural heart disease patients were randomly selected as the study subjects. On the day of admission, blood samples were collected for examination of plasma BNP, blood glucose, blood lipids, etc., and a 6-minute walk test was completed on the same day. Plasma BNP levels were measured by ELISA. Plasma BNP levels and 6min walking distance correlation SPSS for Windows V10.0 package analysis. Results: Plasma BNP levels gradually increased with the severity of heart failure, and had a good correlation with walking distance of 6 min (r = -0.804, P <0.01). Conclusion: Plasma BNP level can determine the severity of heart failure patients, compared with the 6min walk test, has a wider range of clinical value.