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为探讨克山病的心肌损伤与细胞凋亡的关系，采用Ｏｎｃｏｒ公司的细胞凋亡原位检测试剂盒（ＴＵＮＥＬ）对３０例克山病尸检心肌组织进行了检测，其中急型、亚急型、慢型克山病心肌组织各１０例，以因交通事故死亡的５例正常人尸检心肌组织作为对照，结果显示，急型、亚急型、慢型克山病心肌组织中凋亡细胞阳性检出率分别为２／１０、８／１０与７／１０。５例正常心肌组织中，未检出凋亡细胞，以上结果提示：在克山病的发生发展中有凋亡机制参与。
To investigate the relationship between Keshan disease and apoptosis in Keshan disease, 30 cases of Keshan disease autopsy myocardial tissue were detected by Oncor’s TUNEL kit, in which acute, subacute , 10 cases of chronic Keshan disease myocardial tissue, and 5 cases of normal myocardial necrosis due to traffic accident as control. The results showed that acute, sub-acute and chronic Keshan disease positive apoptotic cells in myocardial tissue The detection rate was 2/10, 8/10 and 7 / 10.5 normal myocardial tissue, no apoptotic cells were detected, the above results suggest that: Keshan disease in the occurrence and development of apoptosis mechanisms involved.