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通常认为高血压患者左室首先发生向心性肥厚,事实上左心室的适应性改变远非如此简单。作者采用二维和M型超声心动图测算左室质量和左室壁相对厚度,评价高血压患者左室适应性改变的类型及其与体循环血液动力学、左室负荷及收缩功能的关系。方法对象为165例未经治疗的临界性到重度原发性高血压患者,另选125名年龄、性别配对的健康成人作为对照。相对室壁厚度为2×左室后壁厚度/左室内径,左室质量由Penn法则求得,左室腔形状由短轴/1/2长轴比率描述外周总阻力=平均动脉压/心输出量。左室构型分以下4种,(1)正常构型:左室壁相对厚度及左室质量指数均正常。(2)
It is generally believed that first in patients with hypertension left ventricular concentric hypertrophy, in fact, adaptive changes in the left ventricle is far from so simple. The authors used two-dimensional and M-mode echocardiography to measure left ventricular mass and left ventricular wall thickness to assess left ventricular adaptive changes in patients with hypertension and its relationship with systemic hemodynamics, left ventricular load and systolic function. METHODS: Totally 165 untreated patients with critical to severe essential hypertension were enrolled. A total of 125 healthy adults with matched age and sex were selected as controls. The relative wall thickness was 2 × the thickness of the posterior wall of the left ventricle / the diameter of the left ventricle, and the left ventricular mass was determined by the Penn’s law. The shape of the left ventricle was defined by the ratio of the short axis to the long axis of 1/2. Total peripheral resistance = mean arterial pressure / heart Output. Left ventricular configuration of the following four kinds, (1) normal configuration: the relative thickness of left ventricular wall and left ventricular mass index were normal. (2)