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通过对108例反复呼吸道感染(RRTI)患儿外周血T细胞亚群的检测,发现患儿的CD_4~+细胞及CD_4/CD_8比值明显低于对照组,而CD_8~+细胞则高于对照组。揭示T细胞亚群间的比例失调是RRTI的发病因素之一。提出了调整T细胞亚群功能平衡可能是防治小儿RRTI的重要环节。
The detection of T cell subsets in peripheral blood of 108 patients with recurrent respiratory tract infection (RRTI) showed that the ratio of CD 4 + cells and CD 4 / CD 8 in children with chronic respiratory tract infection was significantly lower than that in control group, while that in CD 8 + cells was higher than that in control group . Revealing the imbalance between T-cell subsets is one of the risk factors for RRTI. It is suggested that adjusting the balance of T cell subsets may be an important part of prevention and treatment of RRTI in children.