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自抗源免疫动物(羊、豚鼠等)之脾脏、淋巴结、腹腔渗出细胞制备之核糖核酸,称为免疫核酸,简称iRNA。自60年代初Fishman、Mannick先后发现能够传递免疫反应作用之后,Alexander在大鼠体内首次证明能传递肿瘤免疫反应。此后,大量研究进一步表明,无论在体外,还是在体内均能传递免疫反应。这种传递可在种间进行,乃至通过动物传递到人。Pilch Y.J,郑昌学等先后将iRNA用于人类肿瘤临床治疗试验。Archer等还发现免疫动物肝RNA制剂也有相似的作用。我们用肿瘤免疫羊制肝RNA进行了类似的研究,无论动物试验,还是临床试用,均取得初步的效果。国内还在抗病毒
Since anti-immune animals (sheep, guinea pigs, etc.) of the spleen, lymph nodes, peritoneal exudate cells prepared RNA, known as the immune nucleic acid, referred to as iRNA. Since the early 60s Fishman, Mannick has been found to be able to pass the immune response, Alexander was the first in rats that can pass the tumor immune response. Since then, a large number of studies further show that, both in vitro and in vivo can transfer the immune response. This transfer can occur between species, even through animals to humans. Pilch Y. J, Zheng Chang Xue and other iRNA will be used in clinical trials of human tumors. Archer et al also found that immunized animal liver RNA preparations also have similar effects. We used a similar strategy to immunize goat liver RNAs for tumors, both for animal testing and for clinical trials, with initial results achieved. Domestic anti-virus