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目的:应用组织多普勒成像(TDI)技术研究节段性早期松弛现象(segmental early relaxation phenomenon,SERP)。方法:103例冠心病患者和50例健康志愿者,根据舒张早期心肌TDI速度曲线将左室各节段分为SERP、收缩期后缩短(PSS)和正常3种舒张方式,分析舒张方式与冠脉狭窄之间的关系。结果:SERP和PSS易出现于冠脉狭窄的节段(OR=4.39和5.59,均P<0.01);但对每一个患者而言,SERP更易出现于冠脉相对狭窄程度最轻的节段(OR=12.53,P<0.01),而PSS不易出现于冠脉相对狭窄程度最轻和中等的节段(OR=0.33和0.41,均P<0.01)。结论:在冠心病患者中舒张早期心肌峰值速度可出现于等容舒张期,这种现象易出现于缺血程度相对较轻的节段。
Objective: To investigate the segmental early relaxation phenomenon (SERP) using tissue Doppler imaging (TDI). Methods: 103 patients with coronary heart disease and 50 healthy volunteers were divided into SERP, PSS and normal diastolic mode according to TDI velocity curve of early diastole, and the relationship between diastolic mode and coronary The relationship between the stenosis. Results: SERP and PSS were predominant in segments of coronary artery stenosis (OR = 4.39 and 5.59, all P <0.01); however, for each patient, SERP was more likely to occur in the lightest segment of coronary arteries OR = 12.53, P <0.01). However, PSS was not found in the lightest and middle coronary arteries (OR = 0.33 and 0.41, both P <0.01). Conclusion: The peak diastolic myocardial peak velocity in patients with coronary heart disease can occur in isovolumic diastolic phase, which is easy to occur in the segment with relatively less ischemia.