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目的观察阿奇霉素片剂在治疗下呼吸道感染中临床疗效 ,体外药物敏感率及病原菌清除情况及治疗的副作用。方法采用阿奇霉素 5 0 0mg,1次 /d,三天口服治疗 ,用药前后检查患者痰液 ,肝肾功能及相应实验室检查 ,记录治疗前后患者症状体征的变化情况及用药过程中出现的不良反应。结果治疗后临床有效率 91.3% ,细菌清除率 82 .35 % ,副作用少。结论在轻、中度下呼吸道感染中阿奇霉素是一种有效的抗生素 ,用药方便、安全、副作用少
Objective To observe the clinical efficacy of azithromycin tablets in the treatment of lower respiratory tract infections, in vitro drug sensitivity and pathogen clearance and treatment side effects. Methods The patients were treated with azithromycin 500 mg once daily for three days before and after treatment. The sputum, liver and kidney function and corresponding laboratory tests were examined before and after treatment. The changes of symptoms and signs of patients before and after treatment were recorded, and the adverse reactions occurred during the medication . Results After treatment, the clinical effective rate was 91.3% and the bacterial clearance rate was 82.35% with few side effects. Conclusion Azithromycin is an effective antibiotic in light and moderate lower respiratory tract infections. It is convenient, safe and has few side effects