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目的本文旨在介绍放疗在合并AIDS的口腔卡勃基氏肉瘤(KS)患者治疗中的有效性。材料与方法1986年6月至1996年12月,亨利蒙德尔医院肿瘤科对62例合并有AIDS的口腔KS患者进行了放射治疗。患者平均年龄39.2岁(28~62岁);男61,女1。治疗前共有44例患者接受过系统的干扰素免疫治疗及化疗等。放疗采用45KV及4MV-X线,剂量10~30.4Gy不等。其中15~15.2Gy50人,30.4Gy3人,10~20Gy9人。根据肿瘤大小及病变部位设野,其中53例采用两侧对穿照射野,9例采用体腔管直对照射。结果在接受DT15~15.2Gy照射的50例患者中,口腔重度反应8人(16%),中度反应9人(18%),轻度反应33人(66%);客观临床缓解率达100%,其中完全缓解率17.8%(11/62),部分缓解率82.2%(51/62),且临床症状获得了良好的改善。结论KS对放疗敏感,对口腔KS放疗是一种有效的姑息治疗手段。DT15Gy足可缓解临床症状并使肿瘤退缩或消退。提倡患者口腔清洁,对患者进行放疗前、中的预防及治疗性的抗真菌治疗很有必要,以改善患者对放疗的耐受性。
The purpose of this article is to describe the effectiveness of radiotherapy in the treatment of patients with oral Cardenosarcoma (KS) who have acquired AIDS. Materials and Methods From June 1986 to December 1996, 62 patients with oral KS with AIDS were treated with radiotherapy at the Department of Oncology, Henri Monde Hospital. The average age of patients 39.2 years (28 to 62 years); male 61, female 1. A total of 44 patients received systemic interferon immunotherapy and chemotherapy before treatment. Radiotherapy using 45KV and 4MV-X line, dose 10 ~ 30.4Gy range. Of which 15 ~ 15.2Gy50 people, 30.4Gy3 people, 10 ~ 20Gy9 people. According to tumor size and location of the site of disease, of which 53 cases were worn on both sides of the radiation field, 9 cases of direct use of body cavity tube irradiation. Results Among the 50 patients receiving DT15 ~ 15.2Gy irradiation, 8 (16%) had oral severe reactions, 9 (18%) moderate reactions and 33 (66%) mild reactions. The objective clinical response rate 100%. The complete remission rate was 17.8% (11/62), the partial remission rate was 82.2% (51/62), and the clinical symptoms were well improved. Conclusion KS is sensitive to radiotherapy and is an effective palliative treatment for oral KS. DT15Gy sufficient to relieve clinical symptoms and tumor regression or regression. To promote oral cleaning of patients, the patient before and after the prevention and treatment of anti-fungal treatment is necessary to improve the patient’s tolerance to radiotherapy.