Proton nuclear magnetic resonance-based metabonomic models for non-invasive diagnosis of liver fibro

• 作 者: Andrea Dória Batista Carl
• 机 构: PostgraduatePrograminTropicalMedicine,DepartmentofGastroenterologyandHepatology,DepartmentofFundamen
• 出 处: 世界肝病学杂志：英文版（电子版）
• 发表日期: 2018年1期
• 关键词: Metabolomics Nuclear magnetic resonance spectroscopy Chronic hepatitis C Liver F

AIM To develop metabonomic models(MMs),using 1H nuclear magnetic resonance(NMR)spectra of serum,to predict significant liver fibrosis(SF:Metavir≥F2),advanced liver fibrosis(AF:METAVIR≥F3)and cirrhosis(C:METAVIR=F4 or clinical cirrhosis)in chronic hepatiti