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流感杆菌和脑膜炎球菌是儿童细菌性脑膜炎常见的致病菌。通常主张以青霉素治疗脑膜炎球菌性脑膜炎,以氨苄青霉素和氯霉素治疗流感杆菌性脑膜炎。但由于耐氨苄青霉素和氯霉素流感杆菌菌株的增加,以及氯霉素对造血系的毒性,必须寻求新的抗菌药替代。本文以羟羧氧酰胺菌素(moxalactam)治疗流感杆菌(25例)和脑膜炎球菌(5例)所致的儿童急性脑膜炎,同时与氨苄青霉素加羟羧氧酰胺菌素治疗组比较作一临床疗效及
Influenza bacilli and meningococci are common bacterial pathogenic bacteria in children with meningitis. It is often advocated that penicillin be used to treat meningococcal meningitis and ampicillin and chloramphenicol to treat influenza bacilli meningitis. However, due to the increase of ampicillin and chloramphenicol-resistant strains of influenza and the toxicity of chloramphenicol to hematopoietic lineages, new antibacterial agents must be sought. In this paper, children with acute meningitis caused by influenza bacilli (25 cases) and meningococci (5 cases) were treated with moxalactam, and compared with ampicillin plus hydroxycarboxamide treatment group Clinical efficacy and