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用免疫学及组织化学方法对７例原发于脊椎骨的非何杰金氏恶性淋巴瘤（ＮＨＬ）进行了回顾性研究。免疫学分型发现了Ｂ细胞型４例、Ｔ细胞型１例、混合型２例。组织学分型低度恶性２例、中度恶性３例、高度恶性２例。其中淋巴浆细胞样型预后最好。术前无一例考虑到本病。鉴别诊断时应除外骨髓瘤、尤文氏瘤、转移性未分化癌和小细胞性骨肉瘤。病变晚期区别是脊椎骨原发还是脊髓原发的ＮＨＬ较为困难。如能肯定为弥漫型或瘤细胞仅限于白质则对前者的确立有帮助。
Seven cases of non-Hodgkin’s lymphoma (NHL) originally found in the vertebrae were retrospectively studied by immunological and histochemical methods. Immunological typing revealed 4 cases of B cell type, 1 case of T cell type, and 2 cases of mixed type. The histological type was low grade in 2 cases, moderate in 3 cases, and high in 2 cases. The best prognosis is lymphoplasmacytic type. No case was considered before the surgery. The differential diagnosis should exclude myeloma, Ewing’s tumor, metastatic undifferentiated carcinoma and small cell osteosarcoma. The late differentiation of the lesions is difficult for the primary spinal or primary spinal NHL. If it can be confirmed that diffuse or tumor cells are limited to white matter, it is helpful for the establishment of the former.