论文部分内容阅读
目的:利用四维CT(4D-CT)和Tumor Loc软件,研究肺下叶(右膈肌层面)距离脊柱不同位置处的呼吸动度。方法:采用放疗专用Philips Brilliance 24排大孔径CT定位机对10例行真空垫固定的患者进行4D-CT模拟定位扫描,将每个呼吸周期的CT图像平均分为10个呼吸时相。通过Tumor Loc软件打开每例患者的10个呼吸时相图像,获得肺下叶内(右膈肌层面)距离脊柱40、50、60、70、80、90 mm处血管中心点在三维方向的位移,分析位移变化及左右距离脊柱相同距离位置处三维方向的相关性。结果:左肺下叶(右膈肌层面),距离脊柱40、50、60、70、80、90 mm位置处,呼吸动度在Z方向(头脚)分别为(9.5±2.5)mm、(9.7±2.6)mm、(9.5±2.5)mm、(9.3±2.3)mm、(9.7±2.5)mm、(9.5±2.6)mm;右肺下叶(右膈肌层面),距离脊柱40、50、60、70、80、90 mm位置处,呼吸动度在Z方向(头脚)分别为(10.5±2.7)mm、(11.4±3.1)mm、(11.3±3.2)mm、(11.5±3.0)mm、(11.6±4.0)mm、(11.7±4.3)mm;左右相同距离位置处,X方向(左右)、Y方向(前后)差异无统计学意义(P>0.05)。左右相同距离位置处,Z方向(头脚)在40、50、60 mm处差异有统计学意义(P分别为0.005、0.007、0.005);Z方向在70、80、90 mm处差异无统计学意义(P>0.05)。结论:应用4D-CT通过Tumor Loc软件可精确测量肺下叶(右膈肌层面)不同位置处在三维方向的呼吸运动度。
OBJECTIVE: To study the respiratory motion of the lower lobe (right diaphragm) at different positions of the spine using 4D CT and Tumor Loc software. Methods: A total of 10 patients undergoing vacuum pad fixation underwent 4D-CT virtual positioning scanning with Philips Brilliance 24-row large aperture CT positioning machine. The CT images of each respiratory cycle were divided equally into 10 respiratory phases. Tumor Loc software was used to open 10 respiratory phase images of each patient to obtain the displacement in the three-dimensional direction of the center of the blood vessel within the lower lobe of the lung (right diaphragm) from the spine at 40, 50, 60, 70, 80 and 90 mm, Analysis of displacement and left and right distance from the spine at the same distance three-dimensional position of the relevance. Results: In the left lower lobe (right diaphragm), the respiration rate was (9.5 ± 2.5) mm and (9.7) in the Z direction (head and foot) respectively at 40, 50, 60, 70, 80 and 90 mm from the spine (9.5 ± 2.5) mm, (9.3 ± 2.3) mm, (9.7 ± 2.5) mm and (9.5 ± 2.6) mm respectively. The lower right lobe (right diaphragm surface) , The respiratory movement in the Z direction (head and foot) were (11.6 ± 3.1) mm, (11.3 ± 3.2) mm and (11.5 ± 3.0) mm at the positions of 70, 80 and 90 mm, (11.6 ± 4.0) mm and (11.7 ± 4.3) mm, respectively. There was no significant difference in X direction (left and right) and Y direction (anteroposterior) at the same distance from left to right (P> 0.05). At the same distance from left to right, the differences of Z direction (head and foot) at 40, 50 and 60 mm were statistically significant (P, 0.005, 0.007 and 0.005 respectively); there was no significant difference in Z direction at 70, 80 and 90 mm Significance (P> 0.05). Conclusion: Using 4D-CT, Tumor Loc software can accurately measure the degree of respiratory motion in different directions in the lower lobe of the lung (right diaphragm) in three dimensions.