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载脂蛋白E存在多种脂蛋白中,参与脂蛋白的转化与代谢过程。载脂蛋白E基因多态性不仅与血脂代谢和动脉粥样硬化密切相关,而且还参与神经细胞的修复和免疫调节。近年来,对载脂蛋白E基因与脑血管疾病的关系进行了深入研究。本文综述了载脂蛋白E基因与血脂关系及在脑血管疾病发生和发展中的研究进展,阐述了载脂蛋白E基因的作用,对这些疾病的防治有重要意义。
Apolipoprotein E exists in a variety of lipoproteins, involved in the transformation and metabolism of lipoproteins. Apolipoprotein E gene polymorphism is not only closely related to lipid metabolism and atherosclerosis, but also involved in nerve cell repair and immune regulation. In recent years, the relationship between apolipoprotein E gene and cerebrovascular disease has been studied in depth. This article reviews the relationship between apolipoprotein E gene and blood lipids and the progress in the development of cerebrovascular disease. The role of apolipoprotein E gene is described, which is of great significance for the prevention and treatment of these diseases.