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牟建军,褚超(西安交通大学医学院第一附属医院心内科,陕西西安710061)一直以来,钠盐摄入量与心血管病风险的关系备受关注,其流行病学证据也大相径庭。一些研究提示钠盐摄入与心血管事件呈连续正相关,而另一些研究认为二者存在J形、甚至U形关联。二者之间的关系在高血压或非高血压群体中是否一致尚不清楚。近期新英格兰杂志发表的一项荟萃分析就该问题进行了探
MU Jian-jun, CHU Chao (Department of Cardiology, the First Affiliated Hospital of Xi’an Jiaotong University School of Medicine, Xi’an 710061, China) The relationship between sodium intake and the risk of cardiovascular diseases has drawn much attention. The epidemiological evidence is also very different. Some studies suggest that there is a continuous and positive correlation between sodium intake and cardiovascular events, while others suggest that there is a J-shape or even a U-shaped association between the two. Whether the relationship between the two are the same in hypertensive or nonhypertensive populations is unclear. A recent meta-analysis by The New England Journal explored the issue