论文部分内容阅读
本文动态测定了36例急性心肌梗塞(AMI)患者血组胺、肌酸磷酸激酶(CPK)及同功酶(CPK-MB)、乳酸脱氢酶(LDH)和天门冬氨酸转氨酶(AST)。结果表明,AMI发病后1～4 (平均2.2±1.2)h血组胺出现异常值,20.2±6.5h上升至峰值,52.6±16.6h下降至正常。36例AMI血组胺峰值平均为4.19±1.35μmol/L,显著高于正常上限(>3.6倍)。血组胺变化明显早于CPK-MB(P<0.01)。14例组胺出现异常值<3h,峰值时间<18h,3例峰值>4.50μmol/L者合并室性心律失常,反之仅占27.27%(P<0.01)。我们认为,血组胺动态测定对AMI早期诊断及缺血性心律失常预测有重要意义。
In this study, the levels of serum amines, creatine phosphokinase (CPK) and isoenzyme (CPK-MB), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) were measured in 36 patients with acute myocardial infarction . The results showed that AMI showed abnormal values of 1 to 4 (average 2.2 ± 1.2) h after the onset of AMI, peaked at 20.2 ± 6.5 hours and decreased to normal at 52.6 ± 16.6 hours. The peak value of histamine in 36 patients with AMI was 4.19 ± 1.35μmol / L, which was significantly higher than the upper limit of normal (> 3.6 times). Blood histamine changes significantly earlier than CPK-MB (P <0.01). Histamine abnormalities in 14 cases <3h, peak time <18h, 3 cases of peak 4.50μmol / L were associated with ventricular arrhythmia, while only 27.27% (P <0.01). In our opinion, the dynamic determination of blood histamine is of great significance for the early diagnosis of AMI and the prediction of ischemic arrhythmia.