Synthesis and Crystal Structure of N′-(4-fluorobenzylidene)-2-(1H-1,2,4-triazole-1-yl)acetohydrazide

• 出 处: Chemical Research in Chinese Universities
• 发表日期: 2006年05期
• 关键词: triazole deviation antifungal coordinates potentially melting intermolecular Ato

N′-(4-fluorobenzylidene)-2-(1H-1,2,4-triazole-1-yl) acetohydrazide was synthesized by the reaction of 4-fluorobenzaldehyde with 2-(1H-1,2,4-triazole-1-yl) acetohydrazide. The structure was confirmed via elemental analysis, MS, 1H NMR, IR, and X-ray diffraction. It crystallized in a monoclinic system with space group P2(1), a=0.4905(1) nm, b=0.8160(2) nm, c=1.4105(3) nm, β=93.33(3)°, Z=2, V=0.5636(2) nm 3, D_ c=1.457 Mg/m 3, μ=0.112 mm -1, F(000)=256, and final R_ 1=0.0685. Several intermolecular hydrogen-bond interactions existed in the crystal structure, facilitating the stabilization of the compound.

N ’- (4-fluorobenzylidene) -2- (1H-1,2,4-triazole-1-yl) acetohydrazide was synthesized by the reaction of 4-fluorobenzaldehyde with 2- 1-yl) acetohydrazide. The structure was confirmed via elemental analysis, MS, 1H NMR, IR, and X-ray diffraction. It crystallized in a monoclinic system with space group P2 (1), a = 0.4905 = 0.8160 (2) nm, c = 1.4105 (3) nm, β = 93.33 (3) °, Z = 2, V = 0.5636 2 nm 3, D c = 1.457 Mg / m 3 and μ = 0.112 mm - 1, F (000) = 256, and final R_ 1 = 0.0685. Several intermolecular hydrogen-bond interactions existed in the crystal structure, facilitating the stabilization of the compound.