Role of NF-κB and cytokine in experimental cancer cachexia

• 作 者: WeiZhou Zhi-WeiJiang JieTian J
• 机 构: DepartmentofSurgery,DepartmentofAnaesthesiology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年7期
• 关键词: 吲哚美辛 恶病质 核因子-ΚB 肿瘤坏死因子-α 白细胞介素-6

AIM: To assess the putative involvement of NF-κB and proinflammatory cytokines in the pathogenesis of cancer cachexia and the therapeutic efficacy of indomethacin (IND)on cachexia.METHODS: Thirty young male BABL/c mice were divided randomly into five grou