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目的分析胺碘酮治疗恶性心律失常的应用效果及给药方式。方法 62例恶性心律失常患者,依据给药方式的差异性分为参照组和研究组,各31例。参照组患者给予胺碘酮静脉注射治疗,研究组患者给予胺碘酮静脉注射联合口服治疗。比较两组患者的治疗效果、并发症发生率以及复发率。结果研究组患者的治疗总有效率为96.8%,与参照组患者的93.5%比较差异无统计学意义(χ~2=0.3503,P>0.05);研究组复发率和并发症发生率分别为3.2%、6.5%,均明显低于参照组的22.6%、29.0%,差异具有统计学意义(χ~2=5.1667,5.4153,P<0.05)。结论胺碘酮治疗恶性心律失常的临床疗效显著,口服联合静脉注射可以减少并发症和复发,具有临床应用价值。
Objective To analyze the effect and administration of amiodarone in the treatment of malignant arrhythmia. Methods Sixty - two patients with malignant arrhythmia were divided into the reference group and the study group according to the difference of administration methods, each of which was 31 cases. Patients in the reference group received intravenous amiodarone, and patients in the study group received intravenous amiodarone and oral treatment. The curative effect, complication rate and relapse rate of the two groups were compared. Results The total effective rate of the study group was 96.8%, which was not significantly different from that of the reference group (93.5%) (χ ~ 2 = 0.3503, P> 0.05). The recurrence rate and complication rate of the study group were 3.2 %, 6.5%, respectively, were significantly lower than the reference group 22.6%, 29.0%, the difference was statistically significant (χ ~ 2 = 5.1667,5.4153, P <0.05). Conclusions The clinical efficacy of amiodarone in the treatment of malignant arrhythmia is significant. Oral and intravenous injection can reduce the complication and recurrence, which has clinical value.