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目的 通过前瞻性系统调查瘫痪病人医院感染发生规律及医院感染对瘫痪病人转归的影响,探讨其防治措施。方法 前瞻性调查。2000年1月～2001年12月神经内科收治的224例瘫痪病人。 结果 发现医院感染60人(68例次),感染率24.59％;感染部位主要是呼吸道;病原菌为革兰氏阴性杆菌占首位;感染在入院后2wk内发生率最高;与瘫痪肌力程度密切相关;≥60岁者发生感染率明显高于<60岁者;感染严重影响到瘫痪病人的预后。 结论 瘫痪病人医院感染发病率与瘫痪肌力程度、卧床时间长、侵入性治疗、不正确使用抗生素、免疫功能下降等因素有关。
Objective To investigate the influence of nosocomial infection on the outcome of nosocomial infection in patients with paralyzed patients and the prevention and treatment of paralyzed patients through prospective systematic investigation. Methods Prospective survey. January 2000 ~ December 2001 Department of Neurology admitted 224 cases of paralyzed patients. The results showed that hospital infection was 60 (68 cases), the infection rate was 24.59%; the infection site was mainly respiratory tract; the pathogen was Gram-negative bacillus; infection occurred most frequently within 2 weeks after admission; it was closely related to the muscle strength of paralyzed ; The infection rate of ≥60 years old was obviously higher than that of <60 years old; the infection seriously affected the prognosis of paralyzed patients. Conclusions The incidence of nosocomial infection in patients with paralysis is related to the degree of paralytic muscle strength, prolonged stay in bed, invasive treatment, improper use of antibiotics and decline of immune function.