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许多研究证实,幽门弯曲菌(Cp)是慢性活动性胃炎的病原体,对十二指肠溃疡(DU)亦有致病作用,但有的学者对此观点仍有异议。铋剂和抗生素对消化性溃疡的Cp都有疗效。作者回顾抗生素对Cp的作用。 McNulty等报告,青霉素、氨苄青霉素、羟氨苄青霉素 磺唑氨苄青霉素在体外试验中,抗Cp的活性最强,其MIC90值范围相似。Kasper等进行体外试验结果表明,头孢菌素抗Cp的活性显著低于青霉素类、红霉素、交沙霉索和roxythromycin的MIC90值也很低。庆大霉素、妥
Many studies confirm that Campylobacter pylori (Cp) is the causative agent of chronic active gastritis and is also pathogenic to duodenal ulcer (DU), but some scholars still disagree. Bismuth and antibiotics have a therapeutic effect on peptic ulcer Cp. The authors review the effect of antibiotics on Cp. McNulty et al. Reported that penicillin, ampicillin, amoxicillin and ampicillin were the most potent anti-Cp agents tested in vitro with similar MIC90 values. Kasper and other in vitro tests showed that cephalosporin anti-Cp activity was significantly lower than that of penicillins, erythromycin, orthomyxomycin and roxythromycin MIC90 value is very low. Gentamicin, proper