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目的:研究盐酸氢吗啡酮和丙泊酚联合用于无痛人流手术的可行性;方法:选择2010年1月——2013年1月自愿行人流手术终止妊娠的早孕女性58例,排除药物过敏史与肝肾重大疾病患者,按照掷骰子法分为联合麻醉组与对照组两个小组,两组患者性别、年龄、体重、孕周等一般资料比较,无统计学方面的意义(p>0.05)。对照组给予单纯丙泊酚麻醉,联合麻醉组联合应用盐酸氢吗啡酮和丙泊酚麻醉,观察麻醉效果及不良反应;结果:联合麻醉组终止妊娠孕妇意识失去时间、苏醒时间、追加丙泊酚比例、不良反应发生率显著优于对照组,且存在显著的统计学意义(p<0.05);结论:盐酸氢吗啡酮和丙泊酚联合用于无痛人流手术效果显著,值得应用于临床。
Objective: To study the feasibility of combination of hydromorphone hydrochloride and propofol for painless abortion. Methods: Fifty-eight pregnant women of the first trimester who terminated voluntary pregnancy with pedestrian flow from January 2010 to January 2013 were excluded, Patients with history and major diseases of liver and kidney were divided into two groups according to the method of dice method, including the joint anesthesia group and the control group. There was no statistical significance in general information such as sex, age, body weight and gestational age between the two groups (p> 0.05 ). The control group was given propofol anesthesia alone, and the combined anesthesia group was given anesthesia with hydromorphone hydrochloride and propofol. The anesthetic effects and adverse reactions were observed. Results: The loss of consciousness, recovery time and propofol (P0.05) .Conclusion: Combination of hydromorphone hydrochloride and propofol for painless abortion is effective and should be applied in clinical practice.