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1940年,Moore等首先发现辅酶Q_(10)(Co-Q_(10))的作用。1957年,Crane等从牛心肌中提纯Co-Q_(10)。以后,人们对其药理作用等进行了较多研究。1965年Yamamura等首先应用Co-Q_(10)治疗心血管疾病。国内江苏泰州生物化学制药厂首先研究成功,1985年通过技术鉴定。目前正日益被临床广泛应用。一、药理作用 Co-Q_(10)是人体细胞中具有重要生化作用的辅酶,在细胞线粒体呼吸链即电子传递系统中起递氢体作用,对一系列酶有激活作用。它
In 1940, Moore and others first discovered the role of coenzyme Q_ (10) (Co-Q_ (10)). In 1957, Crane purified Co-Q_ (10) from bovine myocardium. Later, people conducted more studies on their pharmacological effects. In 1965, Yamamura and other first application of Co-Q_ (10) treatment of cardiovascular disease. Domestic Jiangsu Taizhou biochemical pharmaceutical factory first successful research, passed the technical appraisal in 1985. It is increasingly being widely used in clinical practice. First, the pharmacological effects Co-Q_ (10) is a human body has an important biochemical role in the coenzyme in the mitochondrial respiratory chain that is electron transfer system to play the role of hydrogen delivery, a series of enzymes have an activation effect. it