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AIM:To determine the long-term prevalence of Helicobacterpylori(H pylori)gastritis in patients after partial gastricresection due to peptic ulcer,and to compare the severityof Hpylori-positive gastritis in the corpus mucosa betweenpartial gastrectomy patients and matched controls.METHODS:Endoscopic biopsies were obtained from 57patients after partial gastric resection for histologicalexamination using hematoxylin/eosin and Warthin-Starrystaining.Gastritis was graded according to the updatedSydney system.Severity of corpus gastritis was comparedbetween Hpylori-positive partial gastrectomy patients andHpylori-positive duodenal ulcer patients matched for ageand gender.RESULTS:In partial gastrectomy patients,surgery wasperformed 20 years(median)prior to evaluation.In 25patients(43.8%)Hpyloriwas detected histologically inthe gastric remnant.Gastric atrophy was more common inH pylori-positive compared to H pylori-negative partialgastrectomy patients(P<0.05).The severity of corpusgastritis was significantly lower in Hpylori-positive partialgastrectomy patients compared to duodenal ulcer patients(P<0.01).There were no significant differences in theactivity of gastritis,atrophy and intestinal metaplasiabetween the two groups.CONCLUSION:The long-term prevalence of Hpylorigastritisin the gastric corpus of patients who underwent partialgastric resection due to peptic ulcer disease is comparableto the general population.The expression of Hpylorigastritisin the gastric remnant does not resemble the gastric cancerphenotype.
AIM: To determine the long-term prevalence of Helicobacter pylori (H pylori) gastritis in patients after partial gastric due to peptic ulcer, and to compare the severity of Hpylori-positive gastritis in the corpus mucosa between partial gastrectomy patients and matched controls. METHODS: Endoscopic biopsies were obtained from 57patients after partial gastric resection for histologicalexamination using hematoxylin / eosin and Warthin-Starrystaining. Gastritis was graded according to the updatedSydney system. Severity of corpus gastritis was comparedbetweenHpylori -positive partial gastrectomy patients andHpylori-positive duodenal ulcer patients matched for ageand gender .RESULTS: In partial gastrectomy patients, surgery wasperformed 20 years (median) prior to evaluation. 25patients (43.8%) Hpylori was detected histologically inthe gastric remnant. Genetic atrophy was more common in H pylori-positive compared to H pylori -negative partialgastrectomy patients ( P <0.05). The severity of corpusgastritis wa s significantly lower in Hpylori-positive partialgastrectomy patients compared to duodenal ulcer patients (P <0.01). There were no significant differences in the activity of gastritis, atrophy and intestinal metaplasia between the two groups. CONCLUSION: The long-term prevalence of Hpylorigastritis in the gastric corpus of patients who underwent partialgastric resection due to peptic ulcer disease is comparable to the general population. The expression of Hpylorigastritis in the gastric remnant does not resemble the gastric cancer phenotype.