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目的:探讨肝海绵状血管瘤(CHL)血供来源及经导管肝动脉平阳霉素碘油乳剂(PLE)栓塞硬化治疗的疗效。方法:31例病人59个病灶,采用Seld inger技术行间接门静脉造影和肝动脉造影,分析其血供来源、血窦造影表现等指标及经肝动脉PLE栓塞硬化的疗效分析。结果:本组间接门静脉造影均未发现有肝内门静脉参与CHL供血,肝动脉造影显示1支或多支肝动脉分支参与肿瘤供血,组间比较差异有统计学意义(P<0.01);术前与术后不同时间比较瘤体直径均有明显缩小(P<0.01);无严重并发症发生。结论:经皮肝动脉PLE栓塞硬化治疗CHL简单易行、安全可靠、疗效确切;肝内门静脉未参与供血;CHL血窦丰富程度是影响疗效的关键因素之一。
Objective: To investigate the curative effect of hepatic cavernous hemangioma (CHL) blood supply and transcatheter hepatic artery Pingyangmycin Lipiodol Emulsion (PLE) embolization sclerotherapy. Methods: Totally 59 lesions of 31 patients were studied. Seldinger technique was used to perform indirect portal venography and hepatic arteriography to analyze the source of blood supply, sinusoidal angiography, and the curative effect of PLE embolization. Results: No intrahepatic portal vein was involved in CHL supply in this group of indirect portal venous angiography. Hepatic artery angiography showed that one or more branches of hepatic artery were involved in tumor blood supply. The difference between the two groups was statistically significant (P <0.01) Compared with the time after operation, the diameter of the tumor was significantly reduced (P <0.01); no serious complications occurred. Conclusion: Percutaneous transhepatic arterial PLE embolization is a simple, safe and reliable method for the treatment of CHL. Intrahepatic portal vein is not involved in blood supply. The enrichment of CHL sinusoid is one of the key factors that affect the curative effect.