Microwave-assisted synthesis of α-hydroxy aromatic ketones from α-bromo aromatic ketones in water

• 作 者: Xiang Liu Hai Bo Chen Zheng Gu
• 机 构: School of Chemical and Material Engineering,State Key Laboratory of Bioreactor Engineering,Departmen
• 出 处: 中国化学快报
• 发表日期: 2004年期
• 关键词: α-Hydroxy aromatic ketones α-Bromo aromatic ketones Microwave irradiation
• 基金项目: 国家自然科学基金;This research was financially supported by the National Special Fund for State Key Laboratory of Bioreactor Engineering

A reaction of α-bromo aromatic ketones in water with microwave irradiation gave the corresponding α-hydroxy aromatic ketones in good yields.The use of microwaves was found to significantly improve yields and shorten the reaction time.This reaction afforded a very clean,convenient method for the synthesis of α-hydroxy aromatic ketones.