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目的探讨氯吡格雷联合阿司匹林肠溶片及护理干预在冠心病心绞痛患者中的应用效果。方法选取2015年1月—2016年3月高安市中医院收治的冠心病心绞痛患者90例,随机分为对照组与干预组,各45例。对照组患者给予阿司匹林肠溶片口服治疗,干预组患者给予氯吡格雷联合阿司匹林肠溶片配合护理干预治疗,比较两组患者的临床疗效、心绞痛发作间隔时间、发作次数以及持续时间,观察两组患者药物不良反应发生情况。结果干预组总有效率高于对照组,心绞痛发作间隔时间长于对照组,发作次数少于对照组,持续时间短于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论氯吡格雷联合阿司匹林肠溶片及护理干预在冠心病心绞痛患者中的应用效果明显,能够有效改善患者的临床症状,降低不良反应发生率。
Objective To investigate the effect of clopidogrel combined with aspirin enteric-coated tablets and nursing intervention in patients with coronary heart disease and angina pectoris. Methods 90 patients with coronary heart disease and angina pectoris admitted from January 2015 to March 2016 in Gao’an Hospital of Traditional Chinese Medicine were randomly divided into control group and intervention group, with 45 cases in each group. The patients in the control group were treated with aspirin enteric-coated tablets orally. The patients in the intervention group were given clopidogrel combined with aspirin enteric-coated tablets with nursing intervention. The clinical efficacy, duration of angina pectoris episode, number of seizures and duration were compared between the two groups Adverse drug reactions in patients with the situation. Results The total effective rate in the intervention group was higher than that in the control group. The angina pectoris interval was longer than that in the control group, the number of seizures was less than that in the control group, the duration was shorter than that in the control group, and the incidence of adverse reactions was lower than that in the control group (P < 0.05). Conclusion Clopidogrel combined with aspirin enteric-coated tablets and nursing intervention in patients with coronary heart disease in patients with obvious effect, can effectively improve the clinical symptoms and reduce the incidence of adverse reactions.