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目的探讨胎儿神经母细胞瘤(neuroblastoma,NB)的超声表现及其超声诊断的价值。方法根据成都市妇女儿童中心医院超声科2009年2月至2013年10月产前超声检出的8例胎儿NB及其出生后手术及病理证实,回顾性分析胎儿各个时期的产前超声图像。结果 8例胎儿中,肿瘤位于胸腔/纵隔4例,来源于肾上腺者4例;8例产前均做出正确诊断,胎儿出生后,均由CT、MRI及产后超声证实,手术病例7例,术前超声诊断符合率100%。结论超声可以诊断胎儿NB,为临床早期干预提供依据。
Objective To investigate the ultrasonographic features of fetal neuroblastoma (NB) and its diagnostic value. Methods According to 8 cases of fetal NB detected by ultrasound in Chengdu Women and Children’s Central Hospital from February 2009 to October 2013 and their postoperative biopsy and pathology confirmed by postnatal ultrasound, the prenatal ultrasound images at various stages of fetus were retrospectively analyzed. Results Eight fetuses showed four tumors in the thorax / mediastinum and four in the adrenal gland. Eight of the fetuses were correctly diagnosed before delivery. All of the eight fetuses were confirmed by CT, MRI and postpartum ultrasound. Among the seven cases, Preoperative ultrasound diagnosis in line with the rate of 100%. Conclusion Ultrasound can diagnose fetal NB, providing the basis for clinical early intervention.