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近年来国内外关于口服避孕药对人体细胞SCE的影响虽有报道,但结果不一,且未见对服药10年以上者进行单独报道。本文报道了长期口服短效复方18—甲妇女61名及其中服药10年以上者17名外周血淋巴细胞SCE 的初步观察.材料和方法一、取样来自呼和浩特地区工人、农民和干部的健康育龄妇女112名,无接触电离辐射及有害化学药品史。其中61名长期口服短效复方18—甲,年龄24～50岁,平均38.3岁,服药时间8个月至18年,平均服药时间6.9年;对照组51名,年龄24～50岁,平均36.6岁,未曾服用比短效复方18—甲。
In recent years, domestic and foreign reports on the impact of oral contraceptives on human cell SCE although there are reports, but the results vary, and no medication for more than 10 years were reported separately. This paper reports the long-term oral short-acting compound 18-a women 61 and in which taking more than 10 years of 17 peripheral blood lymphocytes SCE preliminary observation.Materials and methods A sample of healthy women of childbearing age from Hohhot area workers, peasants and cadres 112, non-contact ionizing radiation and history of harmful chemicals. 61 long-term oral short-acting compound 18-A, aged 24 to 50 years old, an average of 38.3 years old, taking a period of 8 months to 18 years, the average medication time of 6.9 years; control group of 51, aged 24 to 50 years, an average of 36.6 Aged, never taking a short-acting compound 18-A.