Methylation profile of the promoter CpG islands of 14“drug-resistance”genes in hepatocellular carcin

• 作 者: ShengDing Bang-DongGong JianYu
• 机 构: TheState-KeyLaboratoryforOncogenesandRelatedGenes
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2004年23期
• 关键词: 甲基化 促进剂 CPG 岛状物 14基因 麻药抵抗作用 肝细胞癌 肿瘤 消化系统 HCC
• 基金项目: Supported by the National High Technology Research and Development Program of China (863 program),No.2002AA2Z3353 and the Science Foundation of Shanghai Municipal Government,No.02DJ14056

AIM: To establish the DNA methylation patterns of the promoter CpG islands of 14 'drug-resistance' genes in hepatocellular carcinoma (HCC).METHODS: The methylation specific polymerase chain reaction in conjunction with sequencing verification was