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多种免疫抑制因子参与抗体的免疫调节,这些因子也常常是多种续发性免疫缺陷病的原因。这些因子可区分为细胞性的和体液性的。细胞性因子包括抑制性巨噬细胞和抑制性T细胞。体液性因子包括血清中的,体液中的(如腹水等)及免疫活性细胞培养液或提取液中的因子。在各类因子中,既有抗原特异性的,也有非特异性的。不过有关这些因子间的异同点,目前尚不完全清楚。对于免疫抑制因子的研究,近年来随着肿瘤免疫学的深入而有很大的进展。
A variety of immunosuppressive factors are involved in the immunoregulation of antibodies, and these factors are often the cause of a number of multiple immunodeficiency diseases. These factors are distinguishable between cellular and humoral. Cytokines include inhibitory macrophages and suppressor T cells. Body fluid factors include those in serum, in body fluids (eg, ascites, etc.), and in immunocompetent cell culture fluids or extracts. Among various factors, both antigen-specific and non-specific. However, the similarities and differences between these factors are not yet fully understood. The research on immunosuppressive factors has made great progress in recent years with the progress of tumor immunology.