论文部分内容阅读
肠道疾病所致的代谢紊乱可以引起尿路结石。这些结石可分为尿酸结石和草酸钙结石两个类型。两者的形成条件不同,有不同的病理生理学机制。炎症性肠病(溃疡性结肠炎和克隆氏病)患者的7～15%并发尿路结石,因肠病作手术后发生率大大增高。尿酸结石:炎症性肠病引起的尿量减少和酸性尿是尿酸结石形成的主要因素。在局限性回肠切除或回结肠转流术后发生率增高。回肠造瘘越靠近端,水和电解质的丧失越严重。回肠内pH值接近8,因此重碳酸盐的丧失导致尿液酸化。尿酸的解离常数(pK)为5.7,尿液的pH每降低1,尿内不溶性尿酸和可溶性尿酸盐
Metabolic disorders caused by intestinal diseases can cause urinary tract stones. These stones can be divided into two types of uric acid stones and calcium oxalate stones. The formation of the two different conditions, there are different pathophysiological mechanisms. 7-15% of patients with inflammatory bowel disease (ulcerative colitis and Crohn’s disease) have urinary tract stones, which are greatly increased after surgery due to enteropathy. Uric acid stones: decreased urinary output caused by inflammatory bowel disease and aciduria is the main factor in the formation of uric acid stones. In the limitations of ileal resection or return of the incidence of postoperative bowel increased. The closer the ileostomy is to the end, the more severe the loss of water and electrolytes. The ileal pH is near 8, so the loss of bicarbonate leads to urine acidification. The uric acid dissociation constant (pK) is 5.7, the urine pH is decreased by 1, the urine insoluble uric acid and soluble urate