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目的 探讨酮康唑洗剂对念珠菌性阴道炎的治疗作用及效果 ,分析阴道 pH值对念珠菌的影响。 方法 每次取 2 %酮康唑洗剂 8ml加入 5 0 0ml 2 5℃左右的温开水 ,混匀后冲洗阴道 4～ 5遍 ,余液擦洗会阴 ,早晚各 1次 ,14天为 1疗程。结果 2疗程治愈 10 0例 ,显效 3例 ,总治愈率及真菌清除率为 97% ,有效率 10 0 %。结论 阴道pH值约为5 .75～ 6.3 5时不利于念珠菌生长 ,酮康唑洗剂能提高阴道粘膜表面的 pH值 ,协同酮康唑起到抑制和杀灭念珠菌的作用。
Objective To investigate the therapeutic effect and effect of ketoconazole lotion on candidal vaginitis and analyze the influence of vaginal pH on Candida. Methods Take 2ml of ketoconazole 8ml each time to add 500ml of warm water about 25 ℃, rinse vagina 4 ~ 5 times after mixing, the remaining liquid scrub the perineum, morning and evening 1, 14 days for a course of treatment. Results 2 courses cured 10 cases, 3 cases markedly effective, the total cure rate and fungal clearance rate was 97%, the effective rate of 10 0%. Conclusion Vaginal pH value of about 5.75 ~ 6.35 is not conducive to the growth of Candida, ketoconazole lotion can increase the pH of the vaginal mucosa surface, synergistic with ketoconazole to inhibit and kill Candida role.