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低温用于治疗脑缺血和重型颅脑外伤已取得一定进展。但脑缺血后将脑温控制到何种程度 ,既能使其发挥最大的护脑作用 ,又不产生严重并发症 ,未见统一标准。本实验以大鼠全脑缺血再灌注模型 ,观察脑缺血后不同程度降温对脑细胞变性坏死和凋亡的影响。1 材料和方法1 .1 实验动物
Low temperature for the treatment of cerebral ischemia and severe craniocerebral injury has made some progress. However, after cerebral ischemia to brain temperature control to what extent, both to maximize their role in protecting the brain, but also does not produce serious complications, no uniform standard. In this experiment, the rat model of global cerebral ischemia-reperfusion, observed after cerebral ischemia varying degrees of cooling on brain cell degeneration and necrosis and apoptosis. 1 Materials and methods 1.1 Experimental animals