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目的探讨桥脑中央髓鞘溶解症(CPM)的影像学表现及临床表现。方法对6例经临床证实的CPM患者进行回顾性分析。结果5例有长期饮酒史,1例营养不良,6例均出现电解质紊乱,4例死亡;MRI表现见桥脑中央对称性长T1长T2信号,DWI呈高信号。结论CPM是临床一种罕见疾病,病理基础是损害桥脑基底中央部,临床表现因受损程度不同而异,影像学检查具有较为特征的MRI表现。
Objective To investigate the imaging findings and clinical manifestations of pontine myelinolysis (CPM). Methods Six cases of clinically confirmed CPM patients were retrospectively analyzed. Results Long-term drinking history was found in 5 cases, malnutrition in 1 case, electrolyte imbalance in 6 cases and death in 4 cases. MRI showed long T1 long T2 signal of central symmetry and DWI high signal. Conclusion CPM is a rare clinical disease. The pathological basis is the damage to the central part of the pons base. The clinical manifestation varies with the degree of injury. Imaging examination has the characteristic MRI manifestations.