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类风湿性关节炎的关节疼痛及肿胀过程之谜现已部分被揭开。伦敦西部的Churing Cross Sunley研究中心的研究人员从分子水平上发现类风湿性关节炎病人关节中的变化。该免疫学研究组负责人Marc Feldmann认为新发现将最终导致对类风湿性关节炎的有效治疗。他希望在1988年年底试验原型疗法,其最终结果可获得治疗此病的新一代药物。在西方国家,患类风湿性关节炎的妇女在2％和3％之间,男性患者近1％。关节炎的首要症状为关节组织(滑液膜)发炎,关节疼痛、肿胀。在疾
The mystery of rheumatoid arthritis pain and swelling is now partially uncovered. Researchers at the Churing Cross Sunley Research Center in western London found molecular changes in the joints of patients with rheumatoid arthritis. Marc Feldmann, head of the immunology team, believes the discovery will eventually lead to an effective treatment of rheumatoid arthritis. He hoped to test prototype therapy by the end of 1988, the end result being a new generation of drugs to treat the disease. In Western countries, women with rheumatoid arthritis are between 2% and 3%, and nearly 1% of males. The first symptom of arthritis is inflammation of the joint tissue (synovial membrane), joint pain and swelling. In the disease