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“八五”期间在食管癌高发区磁县，对其9个乡饮用水源情况进行了全面调查，对水源三氮含量（硝酸盐氮、亚硝酸盐氮、氨氮）连续四年进行监测；对磁县1991～1996年氮肥使用量进行统计，并以省内食管癌低发区赤城作对照。结果表明：防治区水源污染严重，水源三氮含量、氮肥使用量均显著高于赤城，且存在显著差异（P＜0．01）。水源三氮污染与使用氮肥有密切关系，三氮含量与食管癌死亡率呈明显正相关。
During the “Eighth Five-Year Plan” period, in the magnetic county with high incidence of esophageal cancer, a comprehensive investigation was conducted on the drinking water sources in nine townships. The three sources of nitrogen (nitrate nitrogen, nitrite nitrogen, ammonia nitrogen) were monitored for four consecutive years. The use of nitrogen fertilizers in Cixian from 1991 to 1996 was counted and compared with Chicheng, which is a low incidence area for esophageal cancer in the province. The results showed that the water pollution in the prevention and control area was serious, and the water content of trinitrogen and nitrogen fertilizer were significantly higher than those in Chicheng, and there was a significant difference (P<0.01). There is a close relationship between nitrogen pollution in water sources and the use of nitrogen fertilizer, and there is a positive correlation between trinitrogen content and the mortality of esophageal cancer.