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原醛是一种临床综合征,它是由肾上腺自主分泌醛固酮所致,其他方面肾上腺功能正常。主要表现为高血压、低血钾和血肾素减少。成人的原醛常是由肾上腺皮质腺瘤所引起。儿童则多为肾上腺增生所致。双侧肾上腺增生的病例被一些作者称作特发性醛固酮增多或假性醛固酮增多症。有些作者提出肾上腺增生可以不常是双侧性的。近来Suthesland等描述了家族性和可用糖皮质激素治疗逆转的原醛。异位产生醛固酮的肿瘤也有报告、其来源于残余的肾上腺成分。高血压病人中原醛的比率估计从<1%到8%
The original aldehyde is a clinical syndrome, which is caused by autonomic secretion of aldosterone, other aspects of normal adrenal function. Mainly as high blood pressure, hypokalemia and blood renin reduction. The original adult aldehyde is often caused by adrenal cortical adenoma. Children are mostly due to adrenal hyperplasia. Cases of bilateral adrenal hyperplasia are referred to by some authors as idiopathic aldosteronism or pseudohypoosteronemia. Some authors suggest that adrenal hyperplasia can be less often bilateral. Recently Suthesland et al. Described a prototype of aldosterone that reverses familial and glucocorticoid treatment. Ectopic aldosterone-producing tumors are also reported, which are derived from residual adrenal components. The ratio of aldosterone in hypertensive patients is estimated to be from <1% to 8%