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为了验证用来预测只伴有1个淋巴结转移的Ⅲ期结肠癌患者总生存率的预测因子的可靠性,Lin等记录了术前癌胚抗原水平、淋巴结采样状态以及术前辅助化疗的方案,并应用log-rank检验和Cox回归分析方法分析其预后意义。结果:共有363例符合标准的患者被纳入研究,其中位随访期为42个月。其中230例(63.4%)患者接受5-FU化疗方案,76例(20.9%)患者接受奥沙利铂化疗方案,57例(15.7%)患者只接受手术治疗。上述患者5年生存率分别为75%、63%和77%(P=0.823)。多
To verify the reliability of predictors used to predict overall survival in patients with stage III colon cancer with only one lymph node metastasis, Lin et al. Documented precancerous carcinoembryonic antigen levels, lymph node sampling status, and preoperative adjuvant chemotherapy regimens. The prognostic significance was analyzed by log-rank test and Cox regression analysis. Results: A total of 363 eligible patients were included in the study, with a median follow-up of 42 months. Of these, 230 (63.4%) received chemotherapy with 5-FU, 76 (20.9%) received oxaliplatin and 57 (15.7%) received surgery alone. The 5-year survival rates of these patients were 75%, 63% and 77%, respectively (P = 0.823). many