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茶碱治疗呼吸道疾病的有效血浓度为10～20μg/ml。由于茶碱在体内吸收及代谢个体间差异较大,要达到有效血浓度各个体所需剂量悬殊,故临床用药时需监测病人血浆中茶碱浓度。由于静脉多次采血的不便,人们试以唾液代替血液。唾液标本易取、安全、无痛苦,但粘稠度高,分泌量不稳定,常混有下呼吸道分泌物,这就影响了测定结果的准确性。为解决上述问题,作者
Theophylline treatment of respiratory disease effective blood concentration of 10 ~ 20μg / ml. As theophylline absorption and metabolism in the individual differences between individuals larger, to achieve effective blood concentration of the individual required dose disparity, it is necessary to monitor the clinical medication of the patient’s plasma theophylline concentration. Due to the inconvenience of multiple venous blood sampling, people try to replace the blood with saliva. Saliva specimens easy to take, safe, no pain, but high viscosity, unstable secretion, often mixed with lower respiratory secretions, which affects the accuracy of the determination results. To solve the above problem, the author